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Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress
Alpha-ketoglutarate dehydrogenase (α-KGDH) is a highly regulated enzyme, which could determine the metabolic flux through the Krebs cycle. It catalyses the conversion of α-ketoglutarate to succinyl-CoA and produces NADH directly providing electrons for the respiratory chain. α-KGDH is sensitive to r...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569585/ https://ncbi.nlm.nih.gov/pubmed/16321804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1764 |
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