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Antagonistic Regulation of Native Ca(2+)- and ATP-sensitive Cation Channels in Brain Capillaries by Nucleotides and Decavanadate

Regulation by cytosolic nucleotides of Ca(2+)- and ATP-sensitive nonselective cation channels (CA-NSCs) in rat brain capillary endothelial cells was studied in excised inside-out patches. Open probability (P(o)) was suppressed by cytosolic nucleotides with apparent K(I) values of 17, 9, and 2 μM for...

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Detalhes bibliográficos
Main Authors: Csanády, László, Adam-Vizi, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234573/
https://ncbi.nlm.nih.gov/pubmed/15173222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200309008
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