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Antagonistic Regulation of Native Ca(2+)- and ATP-sensitive Cation Channels in Brain Capillaries by Nucleotides and Decavanadate
Regulation by cytosolic nucleotides of Ca(2+)- and ATP-sensitive nonselective cation channels (CA-NSCs) in rat brain capillary endothelial cells was studied in excised inside-out patches. Open probability (P(o)) was suppressed by cytosolic nucleotides with apparent K(I) values of 17, 9, and 2 μM for...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2004
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234573/ https://ncbi.nlm.nih.gov/pubmed/15173222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200309008 |
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