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A Novel Kinetic Assay of Mitochondrial ATP-ADP Exchange Rate Mediated by the ANT

A novel method exploiting the differential affinity of ADP and ATP to Mg(2+) was developed to measure mitochondrial ADP-ATP exchange rate. The rate of ATP appearing in the medium after addition of ADP to energized mitochondria, is calculated from the measured rate of change in free extramitochondria...

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Detalhes bibliográficos
Main Authors: Chinopoulos, Christos, Vajda, Szilvia, Csanády, László, Mándi, Miklós, Mathe, Katalin, Adam-Vizi, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907717/
https://ncbi.nlm.nih.gov/pubmed/19289073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3915
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