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Highly Enantioselective Catalytic Addition of Grignard Reagents to N‐Heterocyclic Acceptors
General methods to prepare chiral N‐heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2‐ and 4‐substituted tetrahydro‐quinolones, dihydro‐4‐pyrid...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772156/ https://ncbi.nlm.nih.gov/pubmed/31257687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906237 |
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