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Catalytic enantioselective addition of Grignard reagents to aromatic silyl ketimines
α-Chiral amines are of significant importance in medicinal chemistry, asymmetric synthesis and material science, but methods for their efficient synthesis are scarce. In particular, the synthesis of α-chiral amines with the challenging tetrasubstituted carbon stereocentre is a long-standing problem...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5196062/ https://ncbi.nlm.nih.gov/pubmed/28008909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13780 |
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