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Highly enantioselective catalytic synthesis of chiral pyridines

General methods to prepare chiral pyridine derivatives are greatly sought after due to their significance in medicinal chemistry. Here, we report highly enantioselective catalytic transformations of poorly reactive β-substituted alkenyl pyridines to access a wide range of alkylated chiral pyridines....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jumde, Ravindra P., Lanza, Francesco, Pellegrini, Tilde, Harutyunyan, Syuzanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727103/
https://ncbi.nlm.nih.gov/pubmed/29233959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01966-7
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