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Highly Enantioselective Catalytic Addition of Grignard Reagents to N‐Heterocyclic Acceptors
General methods to prepare chiral N‐heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2‐ and 4‐substituted tetrahydro‐quinolones, dihydro‐4‐pyrid...
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| Published in: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772156/ https://ncbi.nlm.nih.gov/pubmed/31257687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906237 |
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