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Highly Enantioselective Catalytic Addition of Grignard Reagents to N‐Heterocyclic Acceptors
General methods to prepare chiral N‐heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2‐ and 4‐substituted tetrahydro‐quinolones, dihydro‐4‐pyrid...
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| Pubblicato in: | Angew Chem Int Ed Engl |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772156/ https://ncbi.nlm.nih.gov/pubmed/31257687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906237 |
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