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Enantiospecific Pharmacogenomics of Fluvastatin
The aim of this study was to investigate how variability in multiple genes related to pharmacokinetics affects fluvastatin exposure. We determined fluvastatin enantiomer pharmacokinetics and sequenced 379 pharmacokinetic genes in 200 healthy volunteers. CYP2C9*3 associated with significantly increas...
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| Publicado en: | Clin Pharmacol Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6767327/ https://ncbi.nlm.nih.gov/pubmed/30989645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1463 |
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