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Kinetic basis of metformin-MPP interactions with organic cation transporter OCT2

Organic cation transporter 2 (OCT2) clears the blood of cationic drugs. Efforts to understand OCT2 selectivity as a means to predict the potential of new molecular entities (NMEs) to produce unwanted drug-drug interactions typically assess the influence of the NMEs on inhibition of transport. Howeve...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Renal Physiol
Asıl Yazarlar: Sandoval, Philip J., Morales, Mark, Secomb, Timothy W., Wright, Stephen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766626/
https://ncbi.nlm.nih.gov/pubmed/31313952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00152.2019
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