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Kinetic basis of metformin-MPP interactions with organic cation transporter OCT2
Organic cation transporter 2 (OCT2) clears the blood of cationic drugs. Efforts to understand OCT2 selectivity as a means to predict the potential of new molecular entities (NMEs) to produce unwanted drug-drug interactions typically assess the influence of the NMEs on inhibition of transport. Howeve...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6766626/ https://ncbi.nlm.nih.gov/pubmed/31313952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00152.2019 |
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