Llwytho...

Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2

OCT2 is the entry step for organic cation (OC) secretion by renal proximal tubules. Although many drugs inhibit OCT2 activity, neither the mechanistic basis of their inhibition nor their transport status is generally known. Using representatives of several structural classes of OCT2-inhibitory ligan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Harper, Jaclyn N., Wright, Stephen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971011/
https://ncbi.nlm.nih.gov/pubmed/23034939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00486.2012
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