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Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

Many genome variants shaping mammalian phenotype are hypothesized to regulate gene transcription and/or to be under selection. However, most of the evidence to support this hypothesis comes from human studies. Systematic evidence for regulatory and evolutionary signals contributing to complex traits...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Xiang, Ruidong, van den Berg, Irene, MacLeod, Iona M., Hayes, Benjamin J., Prowse-Wilkins, Claire P., Wang, Min, Bolormaa, Sunduimijid, Liu, Zhiqian, Rochfort, Simone J., Reich, Coralie M., Mason, Brett A., Vander Jagt, Christy J., Daetwyler, Hans D., Lund, Mogens S., Chamberlain, Amanda J., Goddard, Michael E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765237/
https://ncbi.nlm.nih.gov/pubmed/31501319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904159116
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