Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

Many genome variants shaping mammalian phenotype are hypothesized to regulate gene transcription and/or to be under selection. However, most of the evidence to support this hypothesis comes from human studies. Systematic evidence for regulatory and evolutionary signals contributing to complex traits...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Xiang, Ruidong, van den Berg, Irene, MacLeod, Iona M., Hayes, Benjamin J., Prowse-Wilkins, Claire P., Wang, Min, Bolormaa, Sunduimijid, Liu, Zhiqian, Rochfort, Simone J., Reich, Coralie M., Mason, Brett A., Vander Jagt, Christy J., Daetwyler, Hans D., Lund, Mogens S., Chamberlain, Amanda J., Goddard, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765237/
https://ncbi.nlm.nih.gov/pubmed/31501319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904159116
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