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Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice
OBJECTIVES: We previously revealed a role for EZH2 in inducing pro-inflammatory epigenetic changes in lupus CD4+ T cells. In this study, we sought to determine if inhibiting EZH2 ameliorates lupus-like disease in MRL/lpr mice. METHODS: EZH2 expression levels in multiple cell types in lupus patients...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764871/ https://ncbi.nlm.nih.gov/pubmed/31106974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40931 |
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