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On the Contribution of the First Transmembrane Domain to Whole-Cell Current through an ATP-Gated Ionotropic P2X Receptor

Scanning cysteine mutagenesis was used to identify potential pore-forming residues in and around the first transmembrane domains of ionotropic P2X(2) receptor subunits. Twenty-eight unique cysteine-substituted mutants (R28C-Y55C) were individually expressed in HEK293 cells by lipofection. Twenty-thr...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Haines, William R., Voigt, Mark M., Migita, Keisuke, Torres, Gonzalo E., Egan, Terrance M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763184/
https://ncbi.nlm.nih.gov/pubmed/11487611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-16-05885.2001
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