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Gain and Loss of Channel Function by Alanine Substitutions in the Transmembrane Segments of the Rat ATP-Gated P2X(2) Receptor
ATP opens ionotropic P2X channels through a process that is poorly understood. We made an array of mutant rat P2X(2) channels containing unique alanine substitutions in the transmembrane segments with the goal of identifying possible secondary structure and mapping gating domains in the pore. Altera...
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| Publicat a: | J Neurosci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6729769/ https://ncbi.nlm.nih.gov/pubmed/15317863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1423-04.2004 |
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