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Ca(2+) flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus
Activation of ionotropic P2X receptors increases free intracellular Ca(2+) ([Ca(2+)](i)) by initiating a transmembrane cation flux. We studied the “a” and “k” splice variants of the rat purinergic P2X7 receptor (rP2X7aR and rP2X7kR) to exhibit a significant difference in Ca(2+) flux through this cha...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6699846/ https://ncbi.nlm.nih.gov/pubmed/31248985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009666 |
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