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Ca(2+) flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus

Activation of ionotropic P2X receptors increases free intracellular Ca(2+) ([Ca(2+)](i)) by initiating a transmembrane cation flux. We studied the “a” and “k” splice variants of the rat purinergic P2X7 receptor (rP2X7aR and rP2X7kR) to exhibit a significant difference in Ca(2+) flux through this cha...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Samways, Damien S. K., Cox, Jane, Egan, Terrance M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699846/
https://ncbi.nlm.nih.gov/pubmed/31248985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009666
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