Quantifying Ca(2+) Current and Permeability in ATP-gated P2X7 Receptors

ATP-gated P2X7 receptors are prominently expressed in inflammatory cells and play a key role in the immune response. A major consequence of receptor activation is the regulated influx of Ca(2+) through the self-contained cation non-selective channel. Although the physiological importance of the resu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Samways, Damien S. K., Wolf, Kyle, Bowles, Elizabeth A., Richards, Jennifer P., Bruno, Jonathan, Dutertre, Sébastien, DiPaolo, Richard J., Egan, Terrance M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367291/
https://ncbi.nlm.nih.gov/pubmed/25645917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.627810
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