Involvement of Nitric Oxide Released from Microglia–Macrophages in Pathological Changes of Cathepsin D-Deficient Mice

Cathepsin D (CD) deficiency has been shown to induce ceroid-lipofuscin storage in lysosomes of mouse CNS neuron (Koike et al., 2000). To understand the behavior of microglial cells corresponding to these neuronal changes, CD-deficient (CD−/−) mice, which die at approximately postnatal day (P) 25 by...

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Udgivet i:J Neurosci
Main Authors: Nakanishi, Hiroshi, Zhang, Jian, Koike, Masato, Nishioku, Tsuyoshi, Okamoto, Yoshiko, Kominami, Eiki, von Figura, Kurt, Peters, Christoph, Yamamoto, Kenji, Saftig, Paul, Uchiyama, Yasuo
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2001
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ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762915/
https://ncbi.nlm.nih.gov/pubmed/11567042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-19-07526.2001
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