Thyroid functions of mouse cathepsins B, K, and L

Thyroid function depends on processing of the prohormone thyroglobulin by sequential proteolytic events. From in vitro analysis it is known that cysteine proteinases mediate proteolytic processing of thyroglobulin. Here, we have analyzed mice with deficiencies in cathepsins B, K, L, B and K, or K an...

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Hlavní autoři: Friedrichs, Bianca, Tepel, Carmen, Reinheckel, Thomas, Deussing, Jan, von Figura, Kurt, Herzog, Volker, Peters, Christoph, Saftig, Paul, Brix, Klaudia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156100/
https://ncbi.nlm.nih.gov/pubmed/12782676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315990
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