Thyroid functions of mouse cathepsins B, K, and L

Thyroid function depends on processing of the prohormone thyroglobulin by sequential proteolytic events. From in vitro analysis it is known that cysteine proteinases mediate proteolytic processing of thyroglobulin. Here, we have analyzed mice with deficiencies in cathepsins B, K, L, B and K, or K an...

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Главные авторы: Friedrichs, Bianca, Tepel, Carmen, Reinheckel, Thomas, Deussing, Jan, von Figura, Kurt, Herzog, Volker, Peters, Christoph, Saftig, Paul, Brix, Klaudia
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2003
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC156100/
https://ncbi.nlm.nih.gov/pubmed/12782676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315990
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