Thyroid functions of mouse cathepsins B, K, and L

Thyroid function depends on processing of the prohormone thyroglobulin by sequential proteolytic events. From in vitro analysis it is known that cysteine proteinases mediate proteolytic processing of thyroglobulin. Here, we have analyzed mice with deficiencies in cathepsins B, K, L, B and K, or K an...

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Main Authors: Friedrichs, Bianca, Tepel, Carmen, Reinheckel, Thomas, Deussing, Jan, von Figura, Kurt, Herzog, Volker, Peters, Christoph, Saftig, Paul, Brix, Klaudia
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC156100/
https://ncbi.nlm.nih.gov/pubmed/12782676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315990
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