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Thyroid functions of mouse cathepsins B, K, and L

Thyroid function depends on processing of the prohormone thyroglobulin by sequential proteolytic events. From in vitro analysis it is known that cysteine proteinases mediate proteolytic processing of thyroglobulin. Here, we have analyzed mice with deficiencies in cathepsins B, K, L, B and K, or K an...

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Autores principales: Friedrichs, Bianca, Tepel, Carmen, Reinheckel, Thomas, Deussing, Jan, von Figura, Kurt, Herzog, Volker, Peters, Christoph, Saftig, Paul, Brix, Klaudia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC156100/
https://ncbi.nlm.nih.gov/pubmed/12782676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315990
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