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C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABA(B) Receptors

Assembly of fully functional GABA(B) receptors requires heteromerization of the GABA(B(1)) and GABA(B(2))subunits. It is thought that GABA(B(1)) and GABA(B(2)) undergo coiled-coil dimerization in their cytoplasmic C termini and that assembly is necessary to overcome GABA(B(1)) retention in the endop...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Pagano, Adriana, Rovelli, Giorgio, Mosbacher, Johannes, Lohmann, Tania, Duthey, Beatrice, Stauffer, Daniela, Ristig, Dorothee, Schuler, Valerie, Meigel, Ingeborg, Lampert, Christina, Stein, Thomas, Prézeau, Laurent, Blahos, Jaroslav, Pin, Jean-Philippe, Froestl, Wolfgang, Kuhn, Rainer, Heid, Jakob, Kaupmann, Klemens, Bettler, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762227/
https://ncbi.nlm.nih.gov/pubmed/11160389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-04-01189.2001
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