C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABA(B) Receptors

Assembly of fully functional GABA(B) receptors requires heteromerization of the GABA(B(1)) and GABA(B(2))subunits. It is thought that GABA(B(1)) and GABA(B(2)) undergo coiled-coil dimerization in their cytoplasmic C termini and that assembly is necessary to overcome GABA(B(1)) retention in the endop...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Pagano, Adriana, Rovelli, Giorgio, Mosbacher, Johannes, Lohmann, Tania, Duthey, Beatrice, Stauffer, Daniela, Ristig, Dorothee, Schuler, Valerie, Meigel, Ingeborg, Lampert, Christina, Stein, Thomas, Prézeau, Laurent, Blahos, Jaroslav, Pin, Jean-Philippe, Froestl, Wolfgang, Kuhn, Rainer, Heid, Jakob, Kaupmann, Klemens, Bettler, Bernhard
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762227/
https://ncbi.nlm.nih.gov/pubmed/11160389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-04-01189.2001
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