C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABA(B) Receptors

Assembly of fully functional GABA(B) receptors requires heteromerization of the GABA(B(1)) and GABA(B(2))subunits. It is thought that GABA(B(1)) and GABA(B(2)) undergo coiled-coil dimerization in their cytoplasmic C termini and that assembly is necessary to overcome GABA(B(1)) retention in the endop...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pagano, Adriana, Rovelli, Giorgio, Mosbacher, Johannes, Lohmann, Tania, Duthey, Beatrice, Stauffer, Daniela, Ristig, Dorothee, Schuler, Valerie, Meigel, Ingeborg, Lampert, Christina, Stein, Thomas, Prézeau, Laurent, Blahos, Jaroslav, Pin, Jean-Philippe, Froestl, Wolfgang, Kuhn, Rainer, Heid, Jakob, Kaupmann, Klemens, Bettler, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762227/
https://ncbi.nlm.nih.gov/pubmed/11160389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-04-01189.2001
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