C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABA(B) Receptors

Assembly of fully functional GABA(B) receptors requires heteromerization of the GABA(B(1)) and GABA(B(2))subunits. It is thought that GABA(B(1)) and GABA(B(2)) undergo coiled-coil dimerization in their cytoplasmic C termini and that assembly is necessary to overcome GABA(B(1)) retention in the endop...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Pagano, Adriana, Rovelli, Giorgio, Mosbacher, Johannes, Lohmann, Tania, Duthey, Beatrice, Stauffer, Daniela, Ristig, Dorothee, Schuler, Valerie, Meigel, Ingeborg, Lampert, Christina, Stein, Thomas, Prézeau, Laurent, Blahos, Jaroslav, Pin, Jean-Philippe, Froestl, Wolfgang, Kuhn, Rainer, Heid, Jakob, Kaupmann, Klemens, Bettler, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2001
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ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762227/
https://ncbi.nlm.nih.gov/pubmed/11160389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-04-01189.2001
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