Microglial Activation and β-Amyloid Deposit Reduction Caused by a Nitric Oxide-Releasing Nonsteroidal Anti-Inflammatory Drug in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mice

3-4-(2-Fluoro-α-methyl-[1,1′-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester (NCX-2216), a nitric oxide (NO)-releasing derivative of the cyclooxygenase-1-preferring nonsteroidal anti-inflammatory drug (NSAID) flurbiprofen, dramatically reduced both β-amyloid (Aβ) load...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Jantzen, Paul T., Connor, Karen E., DiCarlo, Giovanni, Wenk, Gary L., Wallace, John L., Rojiani, Amyn M., Coppola, Domenico, Morgan, Dave, Gordon, Marcia N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2002
Témata:
ARTICLE
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758281/
https://ncbi.nlm.nih.gov/pubmed/11896164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-06-02246.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky