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Reorganization of Cholinergic Terminals in the Cerebral Cortex and Hippocampus in Transgenic Mice Carrying Mutated Presenilin-1 and Amyloid Precursor Protein Transgenes
Cholinergic deficits are one of the most consistent neuropathological landmarks in Alzheimer’s disease (AD). We have examined transgenic mouse models (PS1(M146L), APP(K670N,M671L)) and a doubly transgenic line (APP(K670N,M671L) + PS1(M146L)) that overexpress mutated AD-related genes [presenilin-1 (P...
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| Gepubliceerd in: | J Neurosci |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Society for Neuroscience
1999
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6786057/ https://ncbi.nlm.nih.gov/pubmed/10087083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-07-02706.1999 |
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