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DNA-PKcs PARylation regulates DNA-PK kinase activity in the DNA damage response
DNA-dependent protein kinase catalytic subunit (-PKcs) is the core protein involved in the non-homologous end-joining repair of double-strand breaks. In addition, it can form a complex with poly(ADP-ribose) polymerase 1 (PARP1), which catalyzes protein PARylation. However, it is unclear how DNA-PKcs...
Salvato in:
| Pubblicato in: | Mol Med Rep |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755157/ https://ncbi.nlm.nih.gov/pubmed/31485633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10640 |
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