DNA-PKcs: A Multi-Faceted Player in DNA Damage Response

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a member of the phosphatidylinositol 3-kinase related kinase family, which can phosphorylate more than 700 substrates. As the core enzyme, DNA-PKcs forms the active DNA-PK holoenzyme with the Ku80/Ku70 heterodimer to play crucial roles in...

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Bibliografische gegevens
Gepubliceerd in:Front Genet
Hoofdauteurs: Yue, Xiaoqiao, Bai, Chenjun, Xie, Dafei, Ma, Teng, Zhou, Ping-Kun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Genetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786053/
https://ncbi.nlm.nih.gov/pubmed/33424929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.607428
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