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DNA-PKcs: A Multi-Faceted Player in DNA Damage Response
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a member of the phosphatidylinositol 3-kinase related kinase family, which can phosphorylate more than 700 substrates. As the core enzyme, DNA-PKcs forms the active DNA-PK holoenzyme with the Ku80/Ku70 heterodimer to play crucial roles in...
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| Pubblicato in: | Front Genet |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7786053/ https://ncbi.nlm.nih.gov/pubmed/33424929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.607428 |
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