The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics

Intervertebral disc degeneration (IDD) is one of the major causes of low back pain. Diabetes is a risk factor for IDD and may aggravate IDD in rats; however, the mechanism is poorly understood. Previously, we demonstrated that apoptosis and senescence were increased in diabetic nucleus pulposus (NP)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Zhang, Zengjie, Lin, Jialiang, Nisar, Majid, Chen, Tingting, Xu, Tianzhen, Zheng, Gang, Wang, Chenggui, Jin, Haiming, Chen, Jiaoxiang, Gao, Weiyang, Tian, Naifeng, Wang, Xiangyang, Zhang, Xiaolei
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754956/
https://ncbi.nlm.nih.gov/pubmed/31583043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7959573
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