Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration

Intervertebral disk degeneration (IDD) is the major cause of low back pain (LBP), which affects 80% of the world’s population. Interleukin 1 beta (IL-1β) is a major inflammatory factor that accelerates disk degeneration, and IL-1β levels increase in degenerative disks. It has recently been reported...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Lin, Jialiang, Chen, Jiaoxiang, Zhang, Zengjie, Xu, Tianzhen, Shao, Zhenxuan, Wang, Xiaobin, Ding, Yuanzhe, Tian, Naifeng, Jin, Haiming, Sheng, Sunren, Gao, Weiyang, Lin, Yan, Zhang, Xiaolei, Wang, Xiangyang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690034/
https://ncbi.nlm.nih.gov/pubmed/31427974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00868
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