Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a complicated pathological condition blamed for low back pain. Mitochondrion is of vital importance for cellular homeostasis, and mitochondrial dysfunction is considered to be one of the major causes of cellular damage. Mitophagy is a cellular process to eli...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Zengjie, Xu, Tianzhen, Chen, Jiaoxiang, Shao, Zhenxuan, Wang, Ke, Yan, Yingchao, Wu, Congcong, Lin, Jialiang, Wang, Haoli, Gao, Weiyang, Zhang, Xiaolei, Wang, Xiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155159/
https://ncbi.nlm.nih.gov/pubmed/30250268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1024-9
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