Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition

Intervertebral disc degeneration (IDD) is a complicated disease in patients. The pathogenesis of IDD encompasses cellular oxidative stress, mitochondrion dysfunction and apoptosis. Melatonin eliminates oxygen free radicals, regulates mitochondrial homoeostasis and function, stimulates mitophagy and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Chen, Yu, Wu, Yanqing, Shi, Hongxue, Wang, Jianle, Zheng, Zengming, Chen, Jian, Chen, Xibang, Zhang, Zengjie, Xu, Daoliang, Wang, Xiangyang, Xiao, Jian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378230/
https://ncbi.nlm.nih.gov/pubmed/30609271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14125
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