Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

Meiotic crossovers (COs) ensure proper chromosome segregation and redistribute the genetic variation that is transmitted to the next generation. Large populations and the demand for genome-wide, fine-scale resolution challenge existing methods for CO identification. Taking advantage of linked-read s...

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Pubblicato in:Nat Commun
Autori principali: Sun, Hequan, Rowan, Beth A., Flood, Pádraic J., Brandt, Ronny, Fuss, Janina, Hancock, Angela M., Michelmore, Richard W., Huettel, Bruno, Schneeberger, Korbinian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754367/
https://ncbi.nlm.nih.gov/pubmed/31541084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12209-2
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