Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

Meiotic crossovers (COs) ensure proper chromosome segregation and redistribute the genetic variation that is transmitted to the next generation. Large populations and the demand for genome-wide, fine-scale resolution challenge existing methods for CO identification. Taking advantage of linked-read s...

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發表在:Nat Commun
Main Authors: Sun, Hequan, Rowan, Beth A., Flood, Pádraic J., Brandt, Ronny, Fuss, Janina, Hancock, Angela M., Michelmore, Richard W., Huettel, Bruno, Schneeberger, Korbinian
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754367/
https://ncbi.nlm.nih.gov/pubmed/31541084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12209-2
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