Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

Meiotic crossovers (COs) ensure proper chromosome segregation and redistribute the genetic variation that is transmitted to the next generation. Large populations and the demand for genome-wide, fine-scale resolution challenge existing methods for CO identification. Taking advantage of linked-read s...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Sun, Hequan, Rowan, Beth A., Flood, Pádraic J., Brandt, Ronny, Fuss, Janina, Hancock, Angela M., Michelmore, Richard W., Huettel, Bruno, Schneeberger, Korbinian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754367/
https://ncbi.nlm.nih.gov/pubmed/31541084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12209-2
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