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Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

Meiotic crossovers (COs) ensure proper chromosome segregation and redistribute the genetic variation that is transmitted to the next generation. Large populations and the demand for genome-wide, fine-scale resolution challenge existing methods for CO identification. Taking advantage of linked-read s...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Sun, Hequan, Rowan, Beth A., Flood, Pádraic J., Brandt, Ronny, Fuss, Janina, Hancock, Angela M., Michelmore, Richard W., Huettel, Bruno, Schneeberger, Korbinian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754367/
https://ncbi.nlm.nih.gov/pubmed/31541084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12209-2
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