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An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy
The paralogous scaffold proteins axin and conductin/axin2 are key factors in the negative regulation of the Wnt pathway transcription factor β-catenin, thereby representing interesting targets for signaling regulation. Polymerization of axin proteins is essential for their activity in suppressing Wn...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6751202/ https://ncbi.nlm.nih.gov/pubmed/31534175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12203-8 |
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