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Sulforaphane inhibits growth and blocks Wnt/β-catenin signaling of colorectal cancer cells

The naturally occurring isothiocyanate sulforaphane (SFN) from cruciferous vegetables is associated with growth inhibition of various cancer types, including colorectal cancer. Colorectal cancer is most frequently driven by hyperactive Wnt/β-catenin signaling. Here, we show that SFN treatment reduce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bernkopf, Dominic B., Daum, Gabriele, Brückner, Martina, Behrens, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188060/
https://ncbi.nlm.nih.gov/pubmed/30338040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26125
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