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Feedback regulation of mitochondrial homeostasis via Wnt/β-catenin signaling

Cellular abundance of mitochondria is dynamically regulated. We could recently show that dysfunctional mitochondria release the phosphatase PGAM family member 5 (PGAM5) into the cytosol, where it interacts with the Wnt signaling-component AXIN1 and dephosphorylates AXIN1-bound β-catenin (CTNNB1) the...

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Publicado en:Mol Cell Oncol
Autores principales: Bernkopf, Dominic B., Behrens, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149705/
https://ncbi.nlm.nih.gov/pubmed/30250905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1458015
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