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Conductin/axin2 and Wnt signalling regulates centrosome cohesion
Activated Wnt/β-catenin signalling is a characteristic of many cancers and drives cell-cycle progression. Here, we report a mechanism linking Wnt/β-catenin signalling to centrosome separation. We show that conductin/axin2, a negative regulator of β-catenin, localizes at the centrosomes by binding to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854593/ https://ncbi.nlm.nih.gov/pubmed/20300119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.23 |
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