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Mouse Axin and Axin2/Conductin Proteins Are Functionally Equivalent In Vivo

Axin is a central component of the canonical Wnt signal transduction machinery, serving as a scaffold for the β-catenin destruction complex. The related protein Axin2/Conductin, although less extensively studied, is thought to perform similar functions. Loss of Axin causes early embryonic lethality,...

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Detalhes bibliográficos
Main Authors: Chia, Ian V., Costantini, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140612/
https://ncbi.nlm.nih.gov/pubmed/15899843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4371-4376.2005
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