Loss of Function but No Gain of Function Caused by Amino Acid Substitutions in the Hexapeptide of Hoxa1 In Vivo

Homeodomain containing transcription factors of the Hox family play critical roles in patterning the anteroposterior embryonic body axis, as well as in controlling several steps of organogenesis. Several Hox proteins have been shown to cooperate with members of the Pbx family for the recognition and...

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Autors principals: Remacle, Sophie, Abbas, Leïla, De Backer, Olivier, Pacico, Nathalie, Gavalas, Anthony, Gofflot, Françoise, Picard, Jacques J., Rezsöhazy, René
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516739/
https://ncbi.nlm.nih.gov/pubmed/15367676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8567-8575.2004
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