Loss of Function but No Gain of Function Caused by Amino Acid Substitutions in the Hexapeptide of Hoxa1 In Vivo

Homeodomain containing transcription factors of the Hox family play critical roles in patterning the anteroposterior embryonic body axis, as well as in controlling several steps of organogenesis. Several Hox proteins have been shown to cooperate with members of the Pbx family for the recognition and...

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Detalhes bibliográficos
Main Authors: Remacle, Sophie, Abbas, Leïla, De Backer, Olivier, Pacico, Nathalie, Gavalas, Anthony, Gofflot, Françoise, Picard, Jacques J., Rezsöhazy, René
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516739/
https://ncbi.nlm.nih.gov/pubmed/15367676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8567-8575.2004
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