Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo

Inhibitor of apoptosis proteins (IAPs) c-IAP1 and c-IAP2 were identified as part of the tumor necrosis factor receptor 2 (TNFR2) signaling complex and have been implicated as intermediaries in tumor necrosis factor alpha signaling. Like all RING domain-containing IAPs, c-IAP1 and c-IAP2 have ubiquit...

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Detalhes bibliográficos
Main Authors: Conze, Dietrich B., Albert, Lori, Ferrick, David A., Goeddel, David V., Yeh, Wen-Chen, Mak, Tak, Ashwell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069614/
https://ncbi.nlm.nih.gov/pubmed/15798218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3348-3356.2005
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