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c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival
Cellular inhibitor of apoptosis proteins (c-IAP) 1 and 2 are widely expressed ubiquitin protein ligases that regulate a variety of cellular functions, including the sensitivity of T cells to co-stimulation. 4-1BB is a TNFR family member that signals via a complex that includes TRAF family members an...
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| Izdano u: | Eur J Immunol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562866/ https://ncbi.nlm.nih.gov/pubmed/26096449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445342 |
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