TBK1 Limits mTORC1 by Promoting Phosphorylation of Raptor Ser877

While best known for its role in the innate immune system, the TANK-binding kinase 1 (TBK1) is now known to play a role in modulating cellular growth and autophagy. One of the major ways that TBK1 accomplishes this task is by modulating the mechanistic Target of Rapamycin (mTOR), a master regulator...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Antonia, Ricardo J., Castillo, Johnny, Herring, Laura E., Serafin, D. Stephen, Liu, Pengda, Graves, Lee M., Baldwin, Albert S., Hagan, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748941/
https://ncbi.nlm.nih.gov/pubmed/31530866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49707-8
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